New Study Shows DNA Sequence Protects Against Spinocerebellar Ataxia

Neuronal intranuclear inclusion 3D illustration
Article Summary
  • Miller School researchers have shown that a specific DNA sequence protects people from developing spinocerebellar ataxia 27B.
  • Spinocerebellar ataxia 27B is a rare, neurodegenerative condition caused by tandem repeat expansions in the FGF14 gene.
  • One-third of all people don’t have the DNA sequence that protects against spinocerebellar ataxia 27B.

Gene Patterns Gone Awry

Identifying a Key DNA Sequence

Dr. Stephen Züchner in his lab
Dr. Stephan Züchner
Matt Danzi, Ph.D., in the lab
Matt Danzi, Ph.D.

Working Toward Greater Understanding, Effective Therapies

Tags: Dr. Stephan Zuchner, Gene sequencing, genetics, John P. Hussman Institute for Human Genomics, spinocerebellar ataxia